Welcome to the Biotage Flash Purification Blogs.

Building greener separations into the flash workflow

November 20, 2018 at 3:01 PM / by Greg Saunders posted in flash purification, column chromatography method, greener flash purification, Flash column chromatography

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The synthesis of new chemical entities certainly has a high environmental cost due to the chemicals employed, especially in flash column chromatography, where large quantities of solvents are routinely used. The previous article in this series presented three strategies that can greatly reduce the environmental impact of your flash purifications: (1) purifying more product with less silica, and solvent, (2) making green chemistry work for you, such as changing to more environmentally friendly solvents, and (3) optimizing chromatography with more effective step gradients. Let’s look at how new developments in column design, simplifications in step gradients, and support from a leader in flash column chromatography can help in making your operation greener.

 

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Make researching new chemistries more fun with the right automated flash column chromatography system

November 5, 2018 at 10:00 AM / by John Urh posted in flash purification, automated chromatography system, column chromatography method, Flash column chromatography

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As we saw in a previous article, the most critical and time-consuming part of organic chemistry synthesis is the purification step. Running a column, testing the resulting fraction, and maybe re-running columns takes too much time – time you could use to prepare reactions or research new chemistries. What if your laboratory equipment made it easier for you to focus on amazing khemistry? Let’s find out what is possible with the latest in automated flash column chromatography systems. 
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