Welcome to the Biotage Flash Purification Blogs.

      Are you in control of your Flash Purification?

      January 29, 2019 at 10:33 AM / by Greg Saunders posted in Biotage, flash chromatography, Flash column chromatography, column chromatography, column chromatography method, flash purification

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      Learn more about how to get in control of your Flash Purification.

      With Biotage® Selekt and Sfär chemists can be in full control of Flash Purification. 
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      Dry loading vs. liquid loading, which provides better flash column chromatography results?

      January 23, 2019 at 2:15 PM / by Bob Bickler posted in flash chromatography, silica column, automated chromatography system, sfär

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      When it comes time to purify your reaction mixture or natural product extract, you have a choice to make. Should you simply load your dissolved sample onto your flash column or take the extra step to adsorb your mix onto a sorbent and dry it before loading? The choice can have a major impact on your results.

      In this post, I will share results of work I conducted in my lab, comparing liquid and dry loading a reaction mixture that containing eight major components.

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      Are there benefits to collecting flash chromatography fractions based on multiple UV wavelengths?

      January 8, 2019 at 7:29 PM / by Bob Bickler posted in UV Detection, Selekt

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      UV detection and fractionation is ubiquitous in flash chromatography. It is the default methodology used to detect and collect eluting compounds. Today’s flash chromatography systems offer UV-triggered fractionation on one, two, or a range of wavelengths in order to either increase fractionation specificity, yield, or increase sensitivity. In this post, I will discuss the value of incorporating fractionation based on a wavelength range and two selectable individual wavelengths.

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