Most flash column manufacturers now offer “high performance” flash chromatography columns with the promise of higher loading, increased purity, and even reduced solvent consumption. Working for Biotage, I have made those valid claims for our products as well.
Are so-called “high performance” flash columns worth their higher prices?
March 19, 2019 at 10:05 PM / by Bob Bickler
Webinar: A Roadmap to Successful Chromatography
March 19, 2019 at 10:00 PM / by Bob Bickler
On July 26th, 2018, Bob Bickler, Senior Technical Specialist, recorded a webinar on A Roadmap to Successful Flash Chromatography. To learn more, read the description below as well as watch the recording!
The three reasons you should be using step gradients for flash column chromatography
March 5, 2019 at 9:34 PM / by Bob Bickler
For most synthesis and natural product chemists, flash chromatography is the primary tool for purification and isolation of compounds of interest. Purification methods include flash system defaulted linear gradients (e.g. 0-100%), active gradient modification (on-the-fly) during purification, and unique method creation based one either the chemist’s experience or TLC data (typically a linear gradient).