Welcome to the Biotage Flash Purification Blogs.

    How can flash chromatography UV absorbance spectra be used to identify purified compounds?

    August 25, 2020 at 1:52 PM / by Bob Bickler posted in Chromatography Fundamentals, UV, Spectra

    0 Comments

    As chemists, our job is to make new molecules. If our synthetic design works as planned, we will have success and the target product made. As we all know, along with our desired compound, by-products are often created as well. To remove the by-products, the reaction mixture requires purification, typically with flash chromatography.

    Read More

    How should I purify a complex, polar, amide reaction mixture?

    August 12, 2020 at 1:46 PM / by Bob Bickler posted in Amine, Chromatography Fundamentals, ION exchange

    0 Comments

    Synthetic chemists continually seek ways to create novel compounds. Along the way they evaluate reagents, solvents, and reaction conditions giving rise to various reaction products and by-products.

    Read More