Purifying your synthetic product efficiently in high yield with minimal impurities is every chemist’s goal. At discovery-scale, flash chromatography is the go-to purification technique as it is relatively simple and effective.
How to Purify your Target Compound with Minimal Impurities
February 23, 2021 at 2:05 PM / by Bob Bickler posted in Chromatography Fundamentals, purification
How does gradient slope impact flash chromatography loading capacity?
February 9, 2021 at 1:40 PM / by Bob Bickler posted in Chromatography Fundamentals, Reversed-phase, Troubleshooting and Optimization, Scale-Up
For many synthetic chemists the primary purification goal is to isolate as much synthetic product as possible with a minimum of 80% purity. The go-to technique for product isolation is flash purification (flash chromatography), especially for intermediates.