Welcome to the Biotage Flash Purification Blogs.

    How to Purify your Target Compound with Minimal Impurities

    February 23, 2021 at 2:05 PM / by Bob Bickler posted in Chromatography Fundamentals, purification

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    Purifying your synthetic product efficiently in high yield with minimal impurities is every chemist’s goal. At discovery-scale, flash chromatography is the go-to purification technique as it is relatively simple and effective.

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    How does gradient slope impact flash chromatography loading capacity?

    February 9, 2021 at 1:40 PM / by Bob Bickler posted in Chromatography Fundamentals, Reversed-phase, Troubleshooting and Optimization, Scale-Up

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    For many synthetic chemists the primary purification goal is to isolate as much synthetic product as possible with a minimum of 80% purity. The go-to technique for product isolation is flash purification (flash chromatography), especially for intermediates.

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