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      Which injection solvents should I use for reversed-phase flash purification?

      September 20, 2019 at 8:21 PM / by Bob Bickler posted in DMF, reversed-phase, DMSO, dissolution


      In previous posts I have touched upon various sample loading options and how they impact flash chromatographic performance, primarily in normal-phase flash purification. As the use of reversed-phase flash chromatography has steadily increased over the past few years I thought it would be a good idea to discuss one of the most important factors impacting its success.

      In this post I discuss the results of some of my original research studying the impact of injection solvent choice on reversed-phase flash separations.

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