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    Why does my silica flash chromatography column get hot?

    December 23, 2020 at 3:16 PM / by Bob Bickler posted in silica, heat


    Silica is the most commonly used sorbent for flash column chromatography. When solvent is pumped through a column packed with dry silica you may notice it gets warm and sometimes down right hot!

    In this post I will attempt to explain why this phenomena occurs.

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