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    Does Size Really Matter in Flash Chromatography? Part 2

    January 7, 2020 at 8:46 PM / by Bob Bickler posted in Media, Load, surface area, particle size


    In a previous post I talked about column size, specifically long-thin versus short-fat and the impact of the cartridge’s dimensions on purification performance. With that comparison I showed that in preparative chromatography, purification efficiency is more about the amount of silica than column dimensions. Cartridges of different dimensions containing the same amount of the same media will provide the same separation efficiency.

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