Sometimes we find ourselves having to make decisions fast, and act even faster - especially in situations like the one we live in today, where there is a high degree of uncertainty.  In this kind of situation it is ideal to find a partner that is willing to share the risk with us, so that the long-term consequences of a decision made in times of uncertainty are not going to make us regret our choice when things get back to normal.

Biotage, pioneers in flash chromatography, started packing columns with silica for flash purification 30 than years ago. Site director Chris Williams tells the story of packing columns - "part science and part art" and high quality across the whole process.

Discovery chemistry labs synthesizing new molecular entities (NMEs) are under pressure to improve their productivity. Optimizing the design-make-test-analyze (DMTA) cycle in the discovery process means ensuring the slow, iterative make step in the process is faster, more predictable and less time-consuming. Although both synthesis and purification in the make step are regarded as most challenging, it is purification that is the most critical aspect of the chemists work. Chemists cannot afford to spend the majority of their time and energy purifying target molecules as this slows down the discovery chemistry process. Effective and reliable purification tools and technologies are critical to the step-change needed in the make cycle. Let’s see how this is possible by partnering with reliable vendors.

Pharmaceutical researchers feel real pressure to increase their R&D productivity by ‘doing more with less’. Despite having limited internal resources and specialized expertise, discovery chemistry research labs are expected to be increasingly effective and efficient, and deliver drug targets faster to advance projects rapidly. However, a lack of effective tools and technologies results in low efficiency workflows, with slow and laborious lead generation and optimization as a result. To boost productivity, the iterative cycle of design-make-test-analyze (DMTA) must move to a ‘best-practices’ state to become faster, more predictable and less time-consuming. A key factor is availability of reliable purification systems from dependable vendors.