Welcome to the Biotage Flash Purification Blogs.

    Organic Chemistry Workflow – Typical Steps and Equipment

    November 12, 2019 at 3:04 PM / by Bob Bickler posted in Chromatography, Synthesis, Workflow


    Synthetic organic chemistry is the genesis of new pharmaceutical and commercial chemical products. In short, it is based on the idea that two or more carbon-based compounds can be forced to react using heat, or other energy source, to create a new, novel product – but this we already know.

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    When should I use dry loading instead of liquid loading with flash column chromatography?

    October 4, 2019 at 6:17 PM / by Bob Bickler posted in Chromatography, Small Molecule, Polar, Samplet(R), Synthesis, Workflow, Media, Loading method


    Many microwave assisted organic synthesis (MAOS) reactions use polar solvents such as alcohols, DMF, DMSO, because they absorb and transfer microwave energy very efficiently.  However, the downside of using polar, microwave absorbing solvents is that they can interfere with normal-phase flash chromatography.

    In this post, I discuss why dry loading can be advantageous when purifying polar-solvated reaction mixtures.

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    Biotage® Selekt

    October 1, 2018 at 1:18 PM / by Raffaella Bombarda posted in Chromatography, Workflow


    Konfidence With a Capital "K", That's Why I Selekt Biotage

    The new Biotage® Selekt Flash Purification System is a system you can use with Konfidence. Purification is a fundamental step in discovery research and, as pioneers of automated flash purification, Biotage® is your ideal partner. Our core philosophies of Quality, Reliability and Environmentalism are drawn from our Swedish heritage. Our smart and intuitive design comes from our knowledge of what our customers need each day. You can see why our customers have “Konfidence” with a capital “ K” in our brand.When it comes to purification there are five reasons to Selekt Biotage®.
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